It all started in 1954 when Dr Vladimir Demikhov shocked the public and the world with a surgically created monstrosity; A 2 headed dog. Dr Demikhov had created this two-headed dog by grafting the Head, Shoulders, and Front legs of a puppy and putting the limbs onto a mature German Shepard in the outskirts of Moscow. Dr Vladimir had shocked many reporters and Journalists, The Soviet Union had proudly spoken about the dog being proof of their medical preeminence. Over the span of fifteen years Dr Demikhov had created twenty two-headed dogs, Sadly none of them lived very long due to Tissue Rejection, The longest his two-headed dogs survived was a month. Demikhov explained that his reason for his monstrosities was to practice organ transplants to be implemented in clinical practice on Humans.

A Soviet physician Sergei Bruk-honenko developed a primitive heart-lung machine which he called “Autojector” and he used this machine on a severed dog head alive. In 1928 he displayed his living dog head to the public before an international audience of scientists at the Third Congress of Physiologists of the USSR wanted Dr Bruk-honeko to prove it was actually alive, So Dr Bruk-honeko banged a hammer on the table that the dog head was on and the dog had flinched, He had shone light into the dogs eyes and they blinked, he Even fed the dog a piece of cheese and it popped out of the esophageal tube on the other end of the dog. The Dog had been alive for six months until the dog had sadly passed away. Dr Bruk-honeko was the first person to ever design and construct a fully functional heart-lung machine and was the first person to experimentally perform a total perfusion with the heart of the animal isolated from the circulation.